Generally, when I interview North American/European job candidates they must have a university education. Its a filter as much as anything, we may lose some good folks, but given the volume of applicants (1,000+ for most postings & lacking a referral) we need to filter and after five or ten years, the difference in speed of learning/training/development from a degree holder usually becomes more obvious.

When I've interviewed job candidates in Asia, in particular, China, Thailand and Vietnam, I don't usually require, for low & mid level roles, a degree. In part because of education corruption & low quality, but also because many very good or great candidates don't have a "good" degree. Instead they have extensive and very positive work experience that candidates with degrees don't have. In these countries, its the work experience I value much more than education, which is more often than not quite lacking in degree holders (with a few exceptions).