I would have a hard time understanding how other factors would make up a heavier weighting than calories in vs calories out. I am certain there are other factors but I am not certain that those factor have make up the majority.
Sure, happy to explain. Here's one example. "The mechanism of antipsychotics-induced weight gain (AIWG) is generally hypothesized by the alteration of glucose metabolism and increasing cholesterol and triglyceride levels."
https://pmc.ncbi.nlm.nih.gov/articles/PMC9170991/#:~:text=Th....
The problem seems to be that people confuse psychical activity with metabolic activity. The body isn't some kind of linear internal combustion engine. Numerous disease processes, medications etc will alter metabolic activity. A classic example is weight loss due to hypothyroidism.
I am not disagreeing that there are other factors and in some tail cases, like people who take antipsychotics, it may have larger weightings but fundamentally we are talking about caloric intake. I think we largely saying the same thing but with different views.
